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Phosphatase and tensin homolog deleted on chromosome ten (pten) is widely known as a tumor suppressor gene Eeg anomalies and epilepsy are a not so rare clinical manifestation in patients with phosphatase and tensin homolog (pten) variants. It is located on chromosome 10q23 with 200 kb, and has dual activity of both.

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Pten (phosphatase and tensin homolog) is a protein coding gene Insights from molecular dynamics simulations of pten and voltage sensitive. Diseases associated with pten include cowden syndrome 1 and macrocephaly/autism syndrome.

Phosphatase and tensin homolog deleted on chromosome 10 (pten) is a dual phosphatase with both protein and lipid phosphatase activities

Pten was first discovered as a tumor. The inactivation of pten is. Pten, through its lipid phosphatase motif, is known to be an inhibitor of the pi3k/akt/mtor signaling pathway, involved in cell growth, proliferation, and differentiation. Interactions of phosphatase and tensin homologue (pten) proteins with phosphatidylinositol phosphates