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Overviews the t cell processing & immunogenicity prediction tools hosted on the analysis resource.slides available for download on our webs. Assemble two datasets of peptides with similar mhc binding affinity, that are (i) recognized or (ii) not recognized by t cells We present patient and product considerations that should be made in designing appropriate in vitro experiments that evaluate t cell epitopes capable of triggering treatment and outcome.
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This tool uses amino acid properties as well as their position within the peptide to predict the immunogenicity of a class i peptide mhc (pmhc) complex. Class i immunogenicity prediction approach Overviews the t cell processing & immunogenicity prediction tools hosted on the analysis resource
Presented by austin crinklaw (tools research technician) and dr.
Processing predictions are better at identifying naturally processed ligands, but have not been shown to be superior in identifying epitopes compared to mhc binding predictions Major histocompatibility complex (mhc) binding, capacity to be generated as.