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The basic process of cell transplantation in the treatment of spinal cord injury mainly includes three important steps Cell replacement therapy, also referred to as cell transplantation, involves the transplantation of neural progenitor cells (npcs), among other cell types, into the site of injury to restore function. Isolation and extraction of cells, purification and screening in vitro and.
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Isolation and extraction of cells, purification and screening in. Isolation and extraction of cells, purification and. Cell transplantation therapy for spinal cord injury refers to transplanting cells into sci patients by local direct transplantation, transvascular grafting or intrathecal injection for.
In this review, we discuss the five most commonly proposed mechanisms through which cell transplantation is thought to promote functional benefits following sci:.
This review summarizes and analyzes the clinical trials of cell transplantation therapy in spinal cord injury, with the aim of providing a rational foundation for the development. Several scientists have tried to generate neural progenitor/stem cells, motor neurons, oligodendrocyte progenitor cells, and olfactory ensheathing cells in vitro, and then transplant. Cellular transplantation for repair of the injured spinal cord has a rich history with strategies focused on neuroprotection, immunomodulation, and neural reconstruction
